Prof. Dr. Dr. Johannes Bode

Pic of Prof. Dr. Dr. Johannes Bode

Deputy Director – Clinic for Gastroenterology, Hepatology and Infectiology – University Hospital Düsseldorf

Role in LiSyM-Cancer

  • Project leader in C-TIP-HCC
  • Data and samples from time resolved preclinical WD mouse models of MASLD/NAFLD, MASH/NASH, fibrosis, cirrhosis and HCC, co-cultivation models, IF and multicolor flow-cytometry analysis, FACS-based cell sorting, ncounter nanostring technology and single cell sequencing including “CITE-Technology”
  • Provides serum, plasma and whole blood samples obtained during a TIPS procedure in patients with liver cirrhosis; longitudinal peripheral venous serum, plasma and whole blood samples; HCC tissue samples and corresponding controls from tumor surgeries

Expertise

  • Expert in clinical, translational and experimental Hepatology, focus on hepato-immunology
  • Gastroenterology, hepatology, liver cirrhosis & complications
  • Interventional hepatology - in particular transjugular intrahepatic portocaval shunt (TIPS) insertion
  • Diagnostic and interventional endoscopy
  • Liver regeneration
  • MASLD, MetALD, cirrhosis development and hepatobiliary tumors with a focus on pathogenesis of HCC
  • Innate Immunity, Macrophages & macrophage polarization, Acute phase response, signal-transduction focusing on stress-kinase signaling and protease-activated receptors.
  • Pathogen-host interaction
  • Systems biology

Degrees

  • Since 2010, appointed W2-Professor for Hepato-Immunology, Medical Faculty, Heinrich-Heine-University of Düsseldorf
  • 2004, Habilitation in internal medicine, Heinrich Heine University Düsseldorf
  • 1997 Doctorate, Immunopathological Laboratory, Eberhard Karls University of Tübingen
  • 1989-1995 Medical studies at the Eberhard Karls University of Tübingen

Professional Experience

  • Since 2020, Deputy Director, Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf
  • 2012-2020, Head Senior Consultant, Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf
  • 2012 - 2021, Deputy spokesperson and project manager, Collaborative Research Centre 974
  • Since 2007, Specialist in Gastroenterology
  • Since 2005, Senior Physician, Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf
  • 2004-2005, University lecturer (C2), Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf
  • 2004 Specialist in internal medicine
  • 2000-2004 Resident, Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf
  • 1998-2000 DFG fellowship, Institute of Biochemistry, RWTH Aachen University (Director: Prof Dr Peter C. Heinrich)
  • 1996-1998 Trainee doctor, then assistant doctor, Clinic for Gastroenterology, Hepatology and Infectiology, University Hospital Düsseldorf

Honors and Awards (selection)

  • 2005-2010, Heisenberg Fellowship of the DFG
  • 2001, Bennigsen-Foerder Prize of the State of North Rhine-Westphalia
  • 1998-2000, Postdoctoral fellowship from the DFG